Hashimoto's thyroiditis is reported to occur in two varieties, an atrophic variety, perhaps associated with HLA-DR3 gene inheritance, and a goitrous form associated with HLA-DR5
The research is clear
Lonborg J, Kelbaek H, Vejlstrup N, Botker HE, Kim WY, Holmvang L, et al
GLP-1 agonists, which primarily target extrahepatic mechanisms to ameliorate metabolic disorders, when used in conjunction with resmetirom, focusing on intrahepatic mechanisms, offer a complementary approach in the management of MASH and liver fibrosis
It discusses key mechanisms linking gut dysbiosis to joint inflammationincluding molecular mimicry, microbial translocation and immune cell trafficking
English translation: This was a randomized controlled trial with four different treatment groups, and everyone plus their dog knew who was getting what drug and dose