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Possible mechanisms may include anti-inflammatory effects as well as suppression of vascular smooth muscle cell proliferation induced by angiotensin II

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On the contrary, studies in rodents show adverse effects on the kidneys at much lower doses of vitamin E comparable with doses used in human studies

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Effects of drug treatment on spontaneous locomotion in the Open Field General spontaneous activity was measured using a computer tracking system to evaluate if spontaneous activity has gone down after 6-OHDA treatment

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Both medications are contraindicated or require strict precautions in pregnancy, with topiramate now requiring a Pregnancy Prevention Programme for women of childbearing potential

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Armstrong MJ, Gaunt P, Aithal GP et al (2016) Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): a multicentre, double-blind, randomised, placebo-controlled phase 2 study

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