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Intramuscular (IM) injection provides 9095% bioavailability for most KLOW peptides, compared to 7085% for subcutaneous (SubQ) administration

The SURPASS-CVOT and retatrutide Phase 3 cardiovascular trials will generate the datasets that establish whether the dual- and triple-agonist compounds replicate the CV-outcome signal semaglutide produced, exceed it, or diverge from it

Many of the existing studies are based on animal models

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