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N Engl J Med 314(23):14941497 Rocha JF, Vaz-Da-Silva M, Nunes T, Igreja B, Loureiro AI, Bonifcio MJ, Wright LC, Falco A, Almeida L, Soares-Da-Silva P (2012) Single-dose tolerability, pharmacokinetics, and pharmacodynamics of etamicastat (BIA 5453), a new dopamine -hydroxylase inhibitor, in healthy subjects

Researchers have proposed several mechanisms, including direct effects on gene transcription factors and indirect influences through cellular signaling cascades that regulate telomerase activity

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Chen, L., Bi, G., Yao, X., Tan, C., Su, J., Ng, N

GIP receptor activation enhances insulin efficiency, which helps partition nutrients away from fat storage