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J Exp Med (2021) 218:117

The product is delivered periodically through a compounding pharmacy

So for most, the warning does not apply

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Who should NOT take phentermine Phentermine is contraindicated in patients with: Cardiovascular disease including coronary artery disease, prior heart attack, stroke, arrhythmias, congestive heart failure, or uncontrolled hypertension Hyperthyroidism (overactive thyroid) Glaucoma Agitated states or history of drug abuse Pregnancy or breastfeeding MAO inhibitor use phentermine must not be taken within 14 days of stopping an MAO inhibitor medication Hypersensitivity to sympathomimetic amines Severe renal impairment dose reduction to 15mg daily is required for patients with eGFR 1529 mL/min/1.73m Your prescriber will review your full medical history, current medications, blood pressure, and cardiovascular risk before prescribing phentermine

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