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The number of animals in each group was set according to statistical verification and previous studies

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To date, although findings advised that G6PD deficiency may lessen free radicals production in failing myocardium and may decrease the risk of coronary heart disease progression, an increase in oxidative stress along with heart failure is also observed in G6PD deficient failing myocardium [206]

The treatment also up-regulated the reduced glutathione/ oxidized glutathione ratio [78]

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