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Following which, 0.4 M NaOH (250 l) was added and incubated for a further 30 min and read at 492 nm

Its unusual for the FDA to go against the recommendations of the Pharmacy Compounding Advisory Committee (PCAC), but it has happened at least once before

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In Phase I, our main goals will be safety and proving the drug is hitting its target the FAK-paxillin complex in fibrotic liver tissue. Though reversing fibrosis takes time, the researchers are also working to identify biomarkers of target engagement, which could accelerate clinical progress

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