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On the other hand, the activity of MMP-9 also profoundly affects the process of tissue repair and remodeling

Genomic Research Campbell et al

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While the downregulated proteins generally participated in the biological process of production 7 , the 93 upregulated proteins were largely associated with gene expression and macromolecule metabolic processes such as DNA repair and replication and protein synthesis and degradation (Fig

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however, excessive phagocytosis of these aggregates may lead to neuronal damage and disease progression (245)