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Photo-oxidation is exacerbated during retinal degeneration and progressive loss of photoreceptors, as the choroid cannot alter the inflow of oxygen supply in response to the changing retinal environment, so the remaining photoreceptors become exposed to a higher oxygen level 22

At physiologically appropriate levels, they are involved in cell signaling processes

Chronic and post-surgical cases often run 8 to 12 weeks or longer

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The GSH-GPX4 signaling axis is an important intracellular antioxidant pathway, which is essential for maintaining the redox homeostasis in cells

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