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3-Hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMGCR) is recruited for ERAD via insulin-induced genes (INSIGs) and exhibits preferential preference for certain ERAD E3 ubiquitin ligases, exemplified by glycoprotein 78 (gp78), chromosome 8 translocation in renal carcinoma (TRC8), and ring finger protein 145 (RNF145)

Muscle-specific CRISPR/Cas9 dystrophin gene editing ameliorates pathophysiology in a mouse model for Duchenne muscular dystrophy

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