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J Clin Invest 101(3):515520

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These findings highlight putrescine as a regulator of pigmentation and provide new avenues for developing novel treatments for pigmentation disorders

Future Directions and Perspectives It would be interesting to investigate whether GSH supplementation or its depletion ameliorates or aggravates hyperglycaemia- or chronic alcohol-mediated oxidative stress and injury in liver, respectively, and to what degree do the GSH-modulating agents affect the damage due to the parent toxins, i.e

Arnold et al., 2022)