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For any exposure longer than 30 minutes, or if the pen feels noticeably warm, contact PlexusDx's clinical team before injecting to confirm whether the dose is still viable

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This cell population peaked at 3 h pi and reached a minimum at 12 h pi

Due to challenges in medicinal chemistry, one antagonist (VENT-03, targeting cGAS) has been advanced into phase I clinical trials, which aims to evaluate the safety of VENT-03 in healthy volunteers, and subsequent trial plans will target the treatment of autoimmune diseases (118)