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PTEN, a key negative regulator of the PI3K/AKT pathway, dephosphorylates PIP3 back to PIP2, thus inhibiting AKT activation (95)

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Feb 2012;219(4):1099-109

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Consistent with these mechanisms, Allium sativum (garlic) induces oxidative stress by elevating intracellular ROS levels, further suppressing fungal proliferation (Lemar et al., 2005)