In the context of GLP-1 therapy, changes in stomach motility and potential mild gastritis from slower food movement could theoretically contribute to increased hiccup frequency in sensitive individuals
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High-glycemic-index foods (white bread, glucose drinks, white rice) cause rapid insulin spikes and strong somatostatin activation
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Similarly, zinc treatment leads to a change in metabolic profile with beneficial effects on insulin sensitivity in both obese children and adults (130134)