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Prevention strategies for chemotherapy-induced hand-foot syndrome: a systematic review and meta-analysis of prospective randomised trials

Islet amyloid polypeptide (IAPP) IAPP, a protein that is coexpressed and cosecreted with insulin by cells, forms membrane-permeable toxic oligomers and accumulates in the ER under continuous demand for insulin

compared to a low bioavailability of 1-2% when taken orally

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Interplay between bax, reactive oxygen species production, and cardiolipin oxidation during apoptosis

Funding This study was supported by the National Key Research and Development Program of China (2023YFC2411205)