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Cell-Type Resolution: Bulk RNA-seq averages the gene expression of the entire hippocampus

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Low SHBG levels cause an increase in free testosterone (fT) in the blood, which is converted into DHT by the enzyme 5--reductase (184)

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These complexes exploit tumor-selective copper overload (35 times higher than normal cells) to generate site-specific ROS via Fenton-like reactions, where Cu(I) catalyzes H2O2 conversion to hydroxyl radicals, overwhelming cancer cell antioxidant defenses [117]