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Pharmacological determinants in GLP-1RA-Associated cancer risk Differential cancer risk profiles across GLP-1RA subtypes and dosing regimens Existing studies underscore significant differences in the effect of various GLP-1RAs on the risk of specific cancers, such as pancreatic cancer [6,7,8, 26, 27]

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[6] [7] Gastrointestinal disturbances such as nausea, diarrhoea, and abdominal discomfort are frequently reported

Metformin and insulin are the standard options in pregnancy Most women planning pregnancy are advised to take folic acid before conception

7 However, this therapy is time-intensive, requiring frequent visits, involves the other members of the family unit, and can be difficult to coordinate

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