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While European guidelines recommend up to 4 g/day for adults, most of the included studies administered pharmacological doses ranging from hundreds to thousands of micrograms

Semaglutide physiologically mimics the function of endogenous GLP-1 hormone, promoting insulin secretion and suppressing glucagon secretion

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full Phase II efficacy data have not been published in the peer-reviewed literature

These symptoms could indicate dehydration severe enough to affect cardiovascular function, electrolyte imbalances reaching dangerous levels, thyroid dysfunction, or other conditions that require medical intervention