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One key characteristic of gut dysbiosis in Alzheimer's disease is an increased ratio of Firmicutes to Bacteroidetes (F/B ratio)

The risk, however, lies less with the molecule itself than with the quality of the preparation and the conditions of administration: a cluster of seven cases of endotoxin poisoning was described after infusions prepared from contaminated raw material not intended for intravenous use (Johnstone et al., Epidemiology and Infection 2018, PMID 29673413)

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The identification of multiple mycotoxin-degrading enzymes, such as peroxidases, laccases, esterases, and oxidoreductases, has paved the way for transforming mycotoxins into less or non-toxic products through diverse pathways, offering a promising avenue for complete detoxification