Angiotensin ii up-regulates sodium-glucose co-transporter 2 expression and sglt2 inhibitor attenuates ang ii-induced hypertensive renal injury in mice
However, its high sugar content requires caution in diabetics
Elevated glucose flux increases mitochondrial electron pressure, driving excess superoxide generation
10.1046/j.1523-1755.2001.00044.x 125 MeiC.ZhengF
NRF2 also cooperates with components of the transcriptional machinery (i.e., MED16) (Sekine et al, 2016), chromatin remodelers (i.e., BRG1) (Zhang et al, 2006) and chromatin-modifying enzymes (i.e., CBP) (Katoh et al, 2001) to drive target gene expression
Images were captured using a fluorescence microscope (cat