Oh R et al
A pooled analysis of the STEP 1-3 clinical trials found nausea affected roughly 44% of participants on semaglutide 2.4 mg, with most GI symptoms mild to moderate and concentrated in the first weeks of treatment
dissected critical molecular events associated with phase separation of an intrinsically disordered prion-like low-complexity domain of Fused in Sarcoma (FUS), revealed the coexistence of two conformationally distinct subpopulations in the monomeric forms, and described conformational shapeshifting events associated with phase separation of this protein (Joshi et al., 2023)
J Cell Sci 123:20942102 Haren L, Remy MH, Bazin I, Callebaut I, Wright M, Merdes A (2006) NEDD1-dependent recruitment of the gamma-tubulin ring complex to the centrosome is necessary for centriole duplication and spindle assembly
A., Saravanan, P., & Tripathi, G
Not stopping there, Gubras latest breakthrough with the initiation of its Phase 1 clinical trial for GUBamy , a long-acting amylin agonist analogue, marks a significant milestone in obesity therapeutics