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A high prevalence of insulin resistance was identified in a sample of 154 non-diabetic PD patients, with 58% being insulin-resistant as indicated by abnormal Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) scores [157]

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This rare condition can lead to: low plasma carnitine progressive cardiomyopathy, or heart muscle disease skeletal myopathy hypoglycemia hypoammonemia weak muscles in the hips, shoulders upper arms, legs, neck, and jaw muscles Untreated it is fatal

Biomaterials Advances

This gutbrain connection, often called the braingut axis, helps explain why medications targeting appetite and digestion may also influence cravings or reward-related behaviors