10.1111/bph.13549 97 SunJ.LiH.JinY.YuJ.MaoS.SuK.et al (2021)
Tirzepatide may be preferable for patients prioritizing maximum weight loss and willing to pay the higher cost
Note your energy levels, skin clarity, and digestion
In contrast, multiple rodent pulmonary hypertension models demonstrate that GLP-1 receptor agonists, including exendin-4 and liraglutide, reduce vascular remodelling, inflammation, and ventricular hypertrophy via endothelial nitric oxide signalling and suppression of endothelin-1 pathways [68,69,72,73]
These findings are broadly compatible with the possibility that GLP-1 signalling may attenuate cue-driven incentive salience, but they do not yet establish a single dopaminergic mechanism as the definitive explanation for the observed behavioural changes
Oxford University Press, Inc