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Reassignment of the human aldehyde dehydrogenase ALDH8A1 (ALDH12) to the kynurenine pathway in tryptophan catabolism

These two amino acid modifications may help by increasing receptor target affinity and supporting molecular stability for a longer half-life

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Our matched cohorts demonstrated significant balance across racial and ethnic distributions, with White patients constituting the majority (65.4% vs 70.2%, p=0.0627), followed by Black or African American (19.5% vs 17.2%, p=0.2768) and Hispanic or Latino patients (9.0% vs 6.6%, p=0.1164)

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Beker, A