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That's why you should always speak to your doctor or pharmacist before adding any new supplements to your routine, Ngo-Hamilton says

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First, although all included studies were high-quality large-scale RCTs, their small number restricted our ability to explain sources of heterogeneity through subgroup analyses

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Many factors can contribute to mental health changes during weight loss treatment, including dietary restrictions, lifestyle modifications, medication side effects such as nausea affecting quality of life, and the psychological impact of body image changes