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450 EpCAM, a cell surface glycoprotein involved in cell adhesion and signaling, has been proposed as a CSC marker in epithelial cancers

For GLP-1R, residues Y148 1.43b , F230 3.33b , M233 3.36b and R310 5.40b partially occupy the orthosteric stie and form hydrophobic interactions with K197 2.67b , W297 ECL2 and L388 7.43b , as well as stacking with W284 4.60b

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According to the American Diabetes Association (ADA), these are among the two first-line therapies for T2D patients at risk for ischemic heart disease or other atherosclerotic cardiovascular disease

Toxicity refers to the degree to which a substance can harm living organisms