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Hydroquinone-induced exogenous ochronosis is a potential side effect which when present, is difficult to treat

Metformin treatment in diabetes and heart failure: when academic equipoise meets clinical reality

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Low sulfur intake : if one does not consume enough sulfur-containing foods, homocysteine will break down in order to provide much needed cysteine for the body

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An imbalance between the pro-death and pro-survival proteins (also known as pro-apoptotic and anti-apoptotic proteins, respectively) can trigger downstream proteins in this pathway, leading to DNA fragmentation and cell death