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Potential metabolic effects of allulose (requiring further research): Modest reduction in postprandial glucose levels Possible stimulation of endogenous GLP-1 secretion Potential improvement in insulin sensitivity Reduction in overall caloric intake when substituted for sugar Patients should discuss any dietary modifications with their healthcare provider, particularly when managing diabetes or taking glucose-lowering medications

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Catecholamines such as adrenaline also activate the cAMP-PKA pathway

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