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Mechanistically, a 2026 PubMed review points to angiogenesis, collagen synthesis, fibroblast activity, and nitric oxide modulation as the likely pathways
(PubMed) Hudson S, Tabet N
The most frequently reported TEAEs in all three groups were gastrointestinal TEAEs, most of which were mild and similarly distributed between the two respective formulations in each group (Tables 4, 5, 6, respectively)
For patients who have continued tirzepatide throughout the perioperative period (as is now common practice in the UK with appropriate risk assessment), no restart is necessary
doi:10.4330/wjc.v17.i8.107991
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