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however, these methods still only provide partial coverage of the metabolome (Wishart, 2011)

Prolonged use of Vitamin B6 (over 2 months) at high doses exceeding 1g/day can lead to severe peripheral neuropathy, with symptoms including unsteady gait and numbness in the hands and feet

Additionally, the inclusion of inositol in some formulations can affect the solubility and stability of the mixture, thus it's important to follow specific guidelines provided for such cases

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Together, these findings support a strong connection between gut health and brain health in ALS

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