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Additionally, PFOS reduced the levels of voltage-dependent anion channels (VDAC
Materials and methods Cell culture The K-562 and Lenti-X 293T cells were purchased from the American Type Culture Collection (CCL-243, ATCC) and Clontech (#632180), respectively
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Posttranslational modifications mediate the structural diversity of tauopathy strains
In a hemorrhagic stroke model, injecting selenium into the brain boosted the expression of the antioxidant GPX4, thereby protecting the neurons and improving behavior ( in vitro and in vivo ( Gpx4 active site, could lead to fatal postnatal epileptic seizures owing to the loss of parvalbumin-positive interneuron ( Trsp and Gpx4 knockout exhibit significant neurophenotypes, including hyperexcitability, spontaneous epilepsy, and ataxia ( Iron Metabolism and Ferroptosis Iron homeostasis is controlled in cells and systems, such as to provide the iron needed for cells and tissues, thereby avoiding iron overload and iron-related toxicity ( 2+ and Fe 3+ forms, which is used to synthesize metalloproteins to participate in the human body ( Heme and non-heme iron from dietary sources exhibit different absorption abilities in the gut
