52 HruzT.LauleO.SzaboG.WessendorpF.BleulerS.OertleL.et al
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Interestingly, it also stimulates insulin secretion from -cells, but with much lower potency than GLP-1 with the mechanism potentially due to the weak binding of glucagon at GLP-1 receptor site [11]
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Additionally, L-OOH is oxidized by Fe 2+ to generate tremendously reactive lipid alkoxyl radicals (LO), which destroy PUFAs through a chain reaction, leading to membrane injury and cell death (Gaschler and Stockwell, 2017)
[DOI] [PubMed] [Google Scholar] 214.Rhea EM, et al