Consistency: Using the same, appropriate type of syringe for every application ensures that any minuscule systemic error is at least consistent, rather than random and chaotic
Pioglitazone A few patients have asked us about pioglitazone recently, probably in relation to this Reddit post
Seizure risk is a concern for susceptible individuals and requires specialist input
Discrimination index The preference for and therefore recognition of the novel object, the novel arm in the Y maze, or the mouse over the empty cage were assessed by calculating the discrimination index (Ennaceur & Delacour, 1988): The discrimination indices of all genotype and treatment groups were compared individually with a theoretical value of 0, which would indicate no preference for the novel or familiar object, Y maze arm, or cage with mouse over empty cage using a one-sample t test
Statements Data availability statement This population-based study obtained data from the TrinetX platform (accessible at for which third-party restrictions apply to the availability of this data
The primary antibodies used in the experiments were as follows: anti-Nrf2 (1:1,000