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GLP-1R mRNA and GLP-1 immunoreactivity was detected in the VTA and NAc, as well as other reward associated areas including lateral hypothalamus, lateral habenula, hippocampus, and substantia nigra (Merchenthaler et al., Afferent and efferent innervation of the hindbrain GLP-1-producing neurons Unlike many of its gut or fat hormone counterparts (ghrelin or leptin) for which there is little evidence of central production, GLP-1 can be made in the brain

"Even if they're listing the right ingredients, you don't know where these ingredients are from or how they've been transported or handled, which could be really dangerous." Lin and Ramachandran recommend that anyone seeking GLP-1 drugs consult with a physician both before they start and while they're taking the medication to manage potential side effects, ensure safety and to make sure medication they receive is FDA-approved

Sharing this information with them may help prevent possible interactions

(PMC) Creatine is not a weight loss drug

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