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OH is the most dangerous free radical and major culprit in free radicalmediated toxicity in cells.16, 3 Both O2 and OH can individually act on lipid membranes to promote the formation of lipid radical (L) which in the presence of oxygen is capable of generating lipid peroxy radical (LOO)3 (Fig

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While GPR119 activation stimulates GLP-1 secretion in primary duodenal cultures, activation is not absolutely required for GLP-1 secretion as shown by L cell specific knockout (Psichas et al., 2017)

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