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The rate at which a medication is metabolized affects how your body will react to that drug: Too fast, and you may not get the effect you need

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These may be more informative in the case of OCD than in many other conditions, as the placebo response rate in OCD especially in the treatment-refractory cases typically represented in pharmacological augmentation studies is particularly low (McDougle, Epperson, Pelton, Wasylink, & Price, 2000