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As with all therapeutic proteins, there is potential for immunogenicity

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Over-the-counter options like loperamide for diarrhea or polyethylene glycol for constipation can be used, but patients should consult their healthcare provider before regular use

In addition, since 4-HNE inhibits nuclear function of -catenin, which is a key factor for transcriptions required for the expression of oncogenes such as c-MYC and cyclin D1 and other genes involving in tumour initiation and progression [123, 124]

Increases in muscle strength ranged from 24-62% depending on the muscle group

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