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33 This article updates previous articles on this topic by Langan and Zawistoski, 4 and by Oh and Brown

Research article Peer reviewed People Animals

Cytosolic Ca 2 dynamics are finely regulated by influx from intracellular organelles (vacuole, endoplasmic reticulum, mitochondria, plastids) and the plasma membrane via voltage-dependent, mechanosensitive, or ligand-activated channels, whereas efflux is mediated by Ca 2 -ATPases and Ca 2 /H antiporters

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The high dose was titrated to that dose after a week at a dose of 5 mg/160 mg

Liubas et al