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Renal benefits of GLP-1 RA One of the main causes of CKD and end-stage renal disease is T2D [53]

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After enough time, their risk for the symptomatic ASCVD outcomes (i.e

In ARPE-19 cells the addition of glucose increased intracellular ROS levels and lowers the expression of the antioxidant genes SOD2, CAT, and HMOX1

341 Schwann cell injury In DPN, hyperglycemia and oxidative stress lead to Schwann cell dysfunction and apoptosis, resulting in demyelination and impaired nerve conduction