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56,57 Although direct injection of CCND2-overexpressing hPSC-CMs is not applicable in humans due to safety concerns, this strategy underscores the potential of pro-proliferative interventions to significantly increase the efficacy of hPSC transplantation

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Biomed Pharmacother 149:112931 Acknowledgements The authors gratefully acknowledge the financial support of the Vice Presidency for Research and Technology of the Jiroft University of Medical Sciences

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