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Best Pract Res Clin Endocrinol Metab 32(1):1725 Braun D, Schweizer U (2018) Thyroid hormone transport and transporters

Picinni and Ricciotti suggested in 1982, that "the therapeutic effectiveness of Polysaccharide Iron Complex when compared with iron fumarate in the treatment of iron deficiency anemia, appears to be as active as the iron fumarate and as well tolerated, however, it exerted a greater influence on the level of hemoglobin and on the number of red cells..." and that, "it has been exceptionally well tolerated by all patients" (Picinni, L.-Ricciotti, M

de Carvalho, C

A specific enzyme called nicotinamide N-methyltransferase (NNMT) is getting attention for its role in obesity and diabetes

However, it is best to err on the side of safety and dose the iron daily for a few days and then weekly thereafter

doi: 10.3390/ijms25073832