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Nitrous oxide, a commonly used anesthetic, oxidizes and inactivates vitamin B 12 , thus inhibiting both of the vitamin B 12 -dependent enzymes, and can produce many of the clinical features of vitamin B 12 deficiency, such as megaloblastic anemia and neuropathy
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That is, on balance, a positive development for medicine
While there is no clinical data specifically supporting this practice for injection sites, general dermatological principles suggest that well-moisturized skin recovers faster from minor trauma
This includes vegans and vegetarians (as B12 is primarily found in animal products), the elderly, people with gastrointestinal issues such as coeliac or Crohns disease, and individuals who have undergone gastric surgery
