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Other molecules, such as lanifibranor (a pan-PPAR agonist) (Francque et al., 2021[25]) and fibroblast growth factor 21 (FGF-21) analogues (Mantovani et al., 2024[50]

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Pharmacologic management of neuropathic pain: Evidence-based recommendations

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A 1 week IGF-1 infusion decreases arterial insulin concentrations but increases pancreatic insulin content and islet vascularity in fetal sheep

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The 1858 C/T SNP of the PTPN22 gene is a risk factor for HT because it causes an arginine-tryptophan substitution at codon 620 (R620W), because decreased T cell signaling may results in poorer thymic elimination of autoreactive T cells, or an increased function of PTPN22 may lead to a decrease in regulatory T cells (Tregs) responsible for preventing autoimmunity

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