doi:10.4061/2010/157591 Hageman GJ, Stierum RH (2001) Niacin, poly(ADP-ribose) polymerase-1 and genomic stability
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Topiramate mechanism of action is not fully understood, but evidence suggests its effect is due to blocking sodium channels (stops rapid firing), enhancing GABA-mediated inhibition, inhibiting glutamate-mediated excitation, and weakly inhibiting carbonic anhydrase
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